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Study identifies new metric for diagnosing autism

Autism spectrum disorder has yet to be linked to a single cause, due to the wide range of its symptoms and severity. However, a recent study suggests a promising new approach to finding answers, one that could lead to advances in the study of other neurological conditions.

Protecting brain cells with cannabinol

Scientists created four cannabis-derived CBN analogs (chemical look-a-likes) with enhanced neuroprotective properties and potential for therapeutic application in neurological disorders like Alzheimer's, Parkinson's, and traumatic brain injury. Their findings reveal novel aspects of CBN's neuroprotective activity and demonstrate the clinical potential of CBN and value of studying its analogs.

New data identifies trends in accidental opioid overdoses in children

The US saw a 22% decline in rates of prescription-opioid overdose related emergency department (ED) visits in children 17 and younger between 2008 and 2019, but an uptick in the early part of the COVID-19 pandemic, according to a new study. The authors also note that rates of pediatric opioid overdoses remain high in many populations.

Workings of working memory detailed

Investigators have discovered how brain cells responsible for working memory -- the type required to remember a phone number long enough to dial it -- coordinate intentional focus and short-term storage of information.

Adults with congenital heart disease faced higher risk of abnormal heart rhythms

Adults with congenital heart defects were more likely to experience an abnormal, irregular heartbeat, finds a new study.

AI speeds up drug design for Parkinson's by ten-fold

Researchers have used artificial intelligence techniques to massively accelerate the search for Parkinson's disease treatments. The researchers designed and used an AI-based strategy to identify compounds that block the clumping, or aggregation, of alpha-synuclein, the protein that characterises Parkinson's.

Tracking a protein's fleeting shape changes

Researchers have developed a powerful, new technique to generate 'movies' of changing protein structures and speeds of up to 50 frames per second.

Research explores how a father's diet could shape the health of his offspring

A mice study suggests a father's diet may shape the anxiety of his sons and the metabolic health of his daughters before they are even conceived.

Novel robotic training program reduces physician errors placing central lines

More than five million central lines are placed in patients who need prolonged drug delivery, such as those undergoing cancer treatments, in the United States every year, yet the common procedure can lead to a bevy of complications in almost a million of those cases. Researchers developed a robotic simulation training program to provide trainee physicians with more practice on the procedure. A year after deploying the program the team found that all complication types -- mechanical issues, infections and blood clots -- were significantly lower.

Researchers uncover human DNA repair by nuclear metamorphosis

Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

Researchers discover urine-based test to detect head and neck cancer

Researchers have created a urine-based test that detects pieces of DNA fragments released by head and neck tumors. The test could potentially facilitate early detection of this cancer type, which currently does not have a reliable screening method.

Nanoparticle delivery of FZD4 to lung endothelial cells inhibits lung cancer progression and metastases

A recent breakthrough study has shown potential to improve therapeutic outcomes for patients suffering from lung cancers.

Following cellular lineage

Researchers have advanced the understanding of how the cerebral cortex develops by tracing the lineage of certain brain cells.

Gender stereotypes in schools impact on girls and boys with mental health difficulties, study finds

Gender stereotypes mean that girls can be celebrated for their emotional openness and maturity in school, while boys are seen as likely to mask their emotional distress through silence or disruptive behaviors, according to a recent study.

Real-time detection of infectious disease viruses by searching for molecular fingerprinting

Researchers develop breakthrough technology for wide-ranging and ultra-sensitive active nano-spectral sensor, surpassing current limitations.

New treatment method using plasma irradiation promotes faster bone healing

Aiming to shorten fracture recovery times, a research group is focusing on plasma irradiation as a treatment method to speed up bone healing.

Common HIV treatments may aid Alzheimer's disease patients

Scientists have identified promising real-world links between common HIV drugs and a reduced incidence of Alzheimer's disease.

New Inflammatory Bowel Disease testing protocol could speed up diagnosis

Patients with suspected inflammatory bowel disease (IBD) could benefit from better testing protocols that would reduce the need and lengthy wait for potentially unnecessary colonoscopies, a new study has found.

Health behaviors accumulate and remain relatively stable throughout middle adulthood

According to a recent study, either healthier or unhealthier health behaviors cluster among individuals. These health behavior patterns remain relatively stable in middle adulthood and are predicted by several sociodemographic and personality characteristics.

New insights could unlock immunotherapy for rare, deadly eye cancer

New research explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before reinfusing them, can successfully treat this rare and aggressive cancer.

Biodiversity is key to the mental health benefits of nature

New research has found that spaces with a diverse range of natural features are associated with stronger improvements in our mental wellbeing compared to spaces with less natural diversity.

'One ring to rule them all': How actin filaments are assembled by formins

Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing filament. Furthermore, the scientists elucidated the reasons for the different speeds at which the different formins promote this process.

Deadly bacteria show thirst for human blood

Some of the world's deadliest bacteria seek out and feed on human blood, a newly-discovered phenomenon researchers are calling 'bacterial vampirism.' Researchers have found the bacteria are attracted to the liquid part of blood, or serum, which contains nutrients the bacteria can use as food. One of the chemicals the bacteria seemed particularly drawn to was serine, an amino acid found in human blood that is also a common ingredient in protein drinks. The research finding, published in the journal eLife, provides new insights into how bloodstream infections occur and could potentially be treated.

Teen stress may raise risk of postpartum depression in adults

A research team reports that social stress during adolescence in female mice later results in prolonged elevation of the hormone cortisol after they give birth.

Scientists identify cell vulnerability 'fingerprint' related to Parkinson's, Lewy body dementia

A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias. The findings reveal that brain cells with Lewy bodies exhibit a specific gene expression pattern akin to a disease-related fingerprint.

Take it from the rats: A junk food diet can cause long-term damage to adolescent brains

A study on the effects of a junk food diet on rats reinforces scientific understanding about the gut-brain connection.

Family and media pressure to lose weight in adolescence linked to how people value themselves almost two decades later

People who as teenagers felt pressure to lose weight from family or from the media, females, people who are not heterosexual, and people experiencing socioeconomic disadvantage, are most at risk of 'internalized' weight stigma, new research has found.

Illuminating the path to hearing recovery

Scientists aim to uncover the mysteries surrounding a specific receptor protein associated with hearing.

Can animals count?

Researchers have made a groundbreaking discovery regarding number sense in animals by confirming the existence of discrete number sense in rats, offering a crucial animal model for investigating the neural basis of numerical ability and disability in humans.

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